NMN & NAD+List
7 things more NAD+ does for you
One molecule fuels your energy, your DNA repair and the enzymes science links to longer life. It begins to drop around 25, and taking NMN raises it again.
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NAD+ remaining, by age
Show these figures as a table
| Age | NAD+ |
|---|---|
| Around 25 | Begins to drop |
| Mid-30s | 25% gone |
| 50 | 50% gone |
Your cells need energy to do their work, and they need repair to keep doing it.
One molecule is behind both. It’s called NAD+.
NAD+ begins to drop around 25. 25% is gone by your mid-30s, and 50% is gone by 50.
It can be rebuilt. Your body makes NAD+ from a molecule called NMN, and taking NMN raises your NAD+ again.
Here are 7 things NAD+ does for you.
1. Longevity
NAD+ fuels sirtuins, the enzymes science links to longer life. When NAD+ drops, sirtuins shut down.
Sirtuins are a family of proteins that help decide how a cell responds to stress, how it looks after itself, and which genes get switched on and off.
They can’t work without NAD+.
2. DNA repair
NAD+ powers the enzymes that fix tens of thousands of daily DNA breaks. Without enough, the damage compounds into aging.
Tens of thousands of breaks a day sounds alarming. It’s normal, and your cells are built for it.
Repair enzymes work around the clock in every cell, and they run on NAD+. Keep your NAD+ up and they have what they need.
3. Cellular energy
NAD+ is how your mitochondria generate ATP and recycle themselves when they wear out.
Mitochondria are the power plants inside your cells. ATP is the fuel they make, and almost everything you do spends it.
Mitochondria also wear out, and NAD+ is part of how your cells replace them. So more NAD+ means more energy today and healthier mitochondria later.
4. Brain
NAD+ fuels your neurons’ energy and their repair pathways. Brain NAD+ declines significantly with age.
Neurons are some of the hungriest cells you have, and some of the hardest to replace.
They need a steady supply of energy, and they need their repair systems working. NAD+ fuels both.
5. Heart
NAD+ drives energy metabolism and vascular function across your cardiovascular system.
Your heart is the one muscle that never rests. That takes a constant supply of energy, and making energy is what NAD+ does.
Vascular function means your blood vessels. NAD+ supports those too.
6. Cellular cleanup
NAD+ powers autophagy, the system your cells use to clear debris and rebuild from within.
Autophagy is how a cell gets rid of its own worn-out parts and builds fresh ones. The Nobel Prize was awarded in 2016 for discovering how it works.
Think of it as taking out the trash, one cell at a time. NAD+ keeps that system running.
7. Skin
NAD+ supports the cells that build collagen and elastin. When it drops, skin loses its ability to repair and renew.
This is the one you can see in the mirror.
Collagen and elastin keep skin firm and springy. The cells that make them need NAD+ like every other cell you have.
How to raise your NAD+
Your body makes NMN for one purpose: to rebuild NAD+.
NMN converts to NAD+ in a single step and goes straight to work, on all 7 of the jobs above.
Taking NMN has been shown to more than double NAD+ levels, restoring NAD+ to the level it was at age 25. (This is true on average but not for everyone.)
That finding comes from 2 human trials (Igarashi et al., npj Aging, 2022; Yi et al., GeroScience, 2023).
A separate trial found higher doses produced the greatest gains in aerobic capacity (Liao et al., 2021). Doses up to 2,000 mg per day have been studied in controlled trials.
Not every NMN capsule holds the same amount
More than half of the NMN supplements sold today deliver 500 mg or less.
And only the beta form of NMN builds NAD+. A label that just says NMN doesn’t tell you which form is inside.
So it helps to see a lab result. In September 2026, an independent 3rd-party lab measured 6 NMN products, and the 5 competitors in that group delivered between 90% and 104% of their labels.
What varied was the dose. One serving held anywhere from 260.7 mg of NMN to 1,139.6 mg.
The testing was commissioned and paid for by the maker of one of the six products tested.
How NMN-99 compares
NMN-99 was at the top of that group. It measured 1,139.6 mg of NMN per serving, against 1,000 mg on its label.
More than double the NMN of 4 out of the 5 top competitors tested.
It’s made with Uthever, the world’s first patented NMN backed by its own randomized, double-blind, placebo-controlled human trial. It’s verified at 99+% purity in the beta form.
A serving is 1,000 mg, the full clinical-range dose. In a controlled trial, NMN at this level raised blood NAD+ 3.7 times above placebo (Bhasin et al., 2023).
Every batch is tested by an independent 3rd-party lab, and the results are published.
Take 2 capsules daily, with or without food. For best results, take it for a minimum of 4 months and beyond.
It comes with a 180-day money-back guarantee on monthly subscriptions and one-time purchases, and 30 days for a full refund on prepaid 12-month subscriptions. Either way, there’s nothing to send back.
Sources
- Igarashi et al., npj Aging, 2022
- Yi et al., GeroScience, 2023
- Liao et al., 2021
- Bhasin et al., 2023
- Read the lab reports
Brands have paid for promotional consideration in these articles.